3rd Degree Burns and Collagen
3rd Degree Burns and Collagen
Collagen is a type of protein.which
can have a profound influence on the outcome of 3rd Degree Burns, and
deep 2nd degree burns
Fibrous in nature, it connects and supports other bodily tissues, such
as skin, bone, tendons, muscles, and cartilage. It also supports the
internal organs and is even present in teeth. There are more than 25
types of collagens that naturally occur in the body.
collagen is formed mainly by two types of collagen,
type I and type III.
In mammals 25% of proteins in the body are formed by collagen.
most common Collagen is
Type I, present in skin, bones, ligaments, Then,
Type II is present in hyaline cartilage and
Type III occurs with type I in skin as reticular fibrils
and also in smooth muscles.
Type IV is present in basal laminas.(thin base layers)
Type V can be found in basal laminas, dermis, tendons,
bones and fibro-cartilage.
has Collagen got to do with 3rd Degree Burns?
scars are often the side effect of the healing
process of deep bums and represent the greatest complication of the
The main causes of hypertrophic burn scars
the over-production of collagen, and the absence of elastic
Typical Hypertrophic Scar
In hypertrophic scars, the lineal direction of
the collagen mass is upset and the Fibres tend to be cross-linked,
also, elastic fibres are less numerous or absent. These differences
in the make-up of the hypertrophic scar may be the reason why the
scars show an increased stretch resistance.
burns, the dermis is not fully functional, if at all, and wounds
that have been left to heal by themselves without skin grafting can
take several months to heal, leaving a wrinkled, ridgy surface, known
as an Hypertrophic Scar.
That is why split skin grafted
surfaces mature 100% faster than such areas and are cosmetically
much better. Regardless of the Meshing Settings.
Influences in Scar Formation
treatment and therapy.
and extent of the Injury.
of the whole treatment.
compression after healing.
care at home.
Does Collagen have any GOOD Points?
Collagen is one of the main components of most
of the current range of Artificial Skin products.
skin consists of a synthetic epidermis and a collagen-based
The artificial dermis is built with
Collagen fibers arranged in a lattice that act as a template
for the formation of new tissue. Fibroblasts, blood vessels, nerve
fibers, and lymph vessels from surrounding healthy tissue grow into
the Collagen lattice, which is eventually absorbed by the
patient's system, then these cells and structures build a new dermis.
The synthetic epidermis, which acts as a temporary
barrier during this process, is eventually peeled off and replaced
with a split-thickness autograft or with an epidermis cultured in the
laboratory from the patient's own skin cells.
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